⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17224585 | 1.00 | — | — | |
| SCHEMBL4405125 | 0.78 | — | — | |
| SCHEMBL1643317 | 0.76 | — | — | |
| SCHEMBL21594598 | 0.74 | — | — | |
| SCHEMBL2402362 | 0.74 | — | — | |
| SCHEMBL11957439 | 0.73 | — | — | |
| SCHEMBL7662496 | 0.73 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL21594592 | 0.71 | — | — | |
| SCHEMBL265958 | 0.71 | MEN1 (0.36) | — | |
| SCHEMBL15976393 | 0.71 | MEN1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114031572-A | Process for preparing substituted cycloserines | 先正达参股股份有限公司 | 2022-02-11 | — | — | CN | disclosed |
| US-9815803-B2 | Process for the preparation of substituted cycloserines | SYNGENTA PARTICIPATIONS AG (CH) | 2017-11-14 | — | — | US | disclosed |
| US-20170204072-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED CYCLOSERINES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-07-20 | — | — | US | disclosed |
| US-9643938-B2 | Process for the preparation of substituted cycloserines | SYNGENTA PARTICIPATIONS AG (CH) | 2017-05-09 | — | — | US | disclosed |
| EP-3137449-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED CYCLOSERINES | Syngenta Participations AG (CH) | 2017-03-08 | — | — | EP | disclosed |
| US-20170044116-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED CYCLOSERINES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-02-16 | — | — | US | disclosed |
| WO-2015166094-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED CYCLOSERINES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-11-05 | — | — | WO | disclosed |
| US-5750735-A | CHEMICAL INTERMEDIATES FOR ANTIBIOTICS | AMERICAN CYANAMID COMPANY (US) | 1998-05-12 | — | — | US | disclosed |
| US-5623081-A | USING BENZYLOXYACETALDEHYDE DIMETHYL ETHER, HALOGENATED 1-PHENYLMETHOXY-4-PENTEN-2-OL; CYCLIZATION | LIN YANG-I (US) | 1997-04-22 | — | — | US | disclosed |
| US-5602118-A | A 2-((2-SUBSTITUTED ALKYL)FUR-3-YL)-THIO-),3-CARBOXY-2-CARBOPENEM DERIVATIVES; EFFECTIVE AGAINST BETA-LACTAM ANTIBIOTIC-RESISTANT BACTERIA | AMERICAN CYANAMID COMPANY (US) | 1997-02-11 | — | — | US | disclosed |
| EP-0617036-A2 | Novel 2-thiosubstituted carbapenems | AMERICAN CYANAMID COMPANY (US) | 1994-09-28 | — | — | EP | disclosed |