Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 15/20 | 0.42 |
| ▸ | RARB | P10826 | 12/20 | 0.42 |
| ▸ | RXRA | P19793 | 4/20 | 0.42 |
| ▸ | RARA | P10276 | 11/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772694 | 0.80 | RARG (0.42) | RARGRARBRXRARARA | |
| SCHEMBL8662683 | 0.74 | RARB (0.45) | RARGRARBRXRARARA | |
| SCHEMBL8665958 | 0.73 | RARG (0.42) | RARGRARBRXRARARA | |
| SCHEMBL8565216 | 0.72 | WDR5 (0.47) | RARGRARBRXRARARA | |
| SCHEMBL8562392 | 0.72 | RARB (0.42) | RARGRARBRXRARARA | |
| SCHEMBL6294016 | 0.71 | GRIK1 (0.48) | RARGRARBRXRARARA | |
| SCHEMBL8331512 | 0.71 | GRIK1 (0.48) | RARGRARBRXRARARA | |
| SCHEMBL6292577 | 0.70 | RARB (0.51) | RARGRARBRXRARARA | |
| SCHEMBL7630266 | 0.70 | RARB (0.36) | RARGRARBRXRARARA | |
| SCHEMBL6423981 | 0.70 | RARB (0.68) | RARGRARBRXRARARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849923-A | Heterocyclic-substituted naphthalenyl retinobenzoic acid derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-12-15 | — | — | US | disclosed |