Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | PTGFR | P43088 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662795 | 0.84 | MEN1 (0.46) | ALDH1A1KMT2AMEN1FAAHCNR2 | |
| SCHEMBL8692871 | 0.76 | MEN1 (0.40) | ALDH1A1KMT2AMEN1CNR2EPHX2 | |
| SCHEMBL7511260 | 0.74 | MEN1 (0.61) | ALDH1A1KMT2AMEN1FAAHCNR2 | |
| SCHEMBL8459789 | 0.73 | MEN1 (0.45) | ALDH1A1KMT2AMEN1FAAHCNR2 | |
| SCHEMBL8459793 | 0.71 | KMT2A (0.45) | ALDH1A1KMT2AMEN1FAAHCNR2 | |
| SCHEMBL8766427 | 0.71 | RARG (0.61) | ALDH1A1KMT2AMEN1FAAHCNR2 | |
| SCHEMBL8766629 | 0.70 | RARB (0.42) | ALDH1A1KMT2AMEN1EPHX2RARB | |
| SCHEMBL9317856 | 0.69 | MEN1 (0.42) | ALDH1A1KMT2AMEN1FAAHCNR2 | |
| SCHEMBL8767040 | 0.69 | RARB (0.44) | ALDH1A1KMT2AMEN1CNR2RARB | |
| SCHEMBL7929993 | 0.69 | MEN1 (0.51) | ALDH1A1KMT2AMEN1FAAHCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658553-B1 | Polycyclic aromatic compounds, pharmaceutical and cosmetic compositions containing them and uses thereof | CIRD GALDERMA (FR) | 1998-11-04 | — | — | EP | disclosed |