Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 6/20 | 0.40 |
| ▸ | RARG | P13631 | 6/20 | 0.40 |
| ▸ | RARA | P10276 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8459793 | 0.85 | KMT2A (0.45) | MEN1KMT2AMAPTTDP1FAAH | |
| SCHEMBL8766427 | 0.83 | RARG (0.61) | MEN1KMT2AMAPTTDP1FAAH | |
| SCHEMBL8766169 | 0.83 | RARB (0.54) | MEN1KMT2AMAPTTDP1FAAH | |
| SCHEMBL9126577 | 0.81 | KMT2A (0.48) | MEN1KMT2AMAPTTDP1FAAH | |
| SCHEMBL9126806 | 0.81 | RARA (0.47) | MEN1KMT2ATDP1FAAHCNR2 | |
| SCHEMBL9551164 | 0.80 | KMT2A (0.49) | MEN1KMT2AMAPTTDP1RARB | |
| SCHEMBL9122436 | 0.80 | LMNA (0.48) | MEN1KMT2AMAPTTDP1FAAH | |
| SCHEMBL9078763 | 0.78 | RARB (0.50) | MEN1KMT2AMAPTTDP1FAAH | |
| SCHEMBL8396496 | 0.78 | KMT2A (0.45) | MEN1KMT2AMAPTTDP1FAAH | |
| SCHEMBL7511260 | 0.77 | MEN1 (0.61) | MEN1KMT2AMAPTTDP1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584191-A1 | NOVEL AROMATIC AND POLYCYCLIC COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDECINE AND IN COSMETICS. | CIRD GALDERMA (FR) | 1994-03-02 | — | — | EP | claimed |
| EP-0584191-A1 | NOVEL AROMATIC AND POLYCYCLIC COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDECINE AND IN COSMETICS. | CIRD GALDERMA (FR) | 1994-03-02 | — | — | EP | disclosed |