Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818274 | 1.00 | LMNA (0.38) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL8666445 | 1.00 | LMNA (0.38) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL818503 | 1.00 | LMNA (0.38) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL8664730 | 1.00 | LMNA (0.38) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL8670101 | 1.00 | LMNA (0.38) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL819089 | 1.00 | LMNA (0.38) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL8667708 | 1.00 | LMNA (0.38) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL819274 | 1.00 | LMNA (0.38) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL8668872 | 1.00 | LMNA (0.38) | LMNATSHRTHRBDNM1EPHX1 | |
| SCHEMBL8670137 | 1.00 | LMNA (0.38) | LMNATSHRTHRBDNM1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530814-B1 | Method for producing a stereospecific polyolefin | TOSOH CORP (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5489634-A | EFFICIENT SELECTIVE CATALYTIC POLYMERIZATION OF ALPHA-OLEFINS YIELDS HIGH MOLECULAR WEIGHT SPHERICAL PARTICLES HAVING HIGH BULK DENSITY, CONTROLLED PARTICLE SIZE AND MOLECULAR WEIGHT DISTRIBUTION | TOSOH CORPORATION (JP) | 1996-02-06 | — | — | US | disclosed |
| EP-0582943-A2 | Method for producing a polyolefin | TOSOH CORPORATION (JP) | 1994-02-16 | — | — | EP | disclosed |
| EP-0530814-A1 | Method for producing a stereospecific polyolefin | TOSOH CORPORATION (JP) | 1993-03-10 | — | — | EP | disclosed |