Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26596768 | 0.78 | MEN1 (0.37) | MAPTHTTGAAKDM4EGLA | |
| SCHEMBL5795074 | 0.76 | — | — | |
| SCHEMBL11016637 | 0.74 | IDO1 (0.35) | ALDH1A1RECQLHPGDIDO1 | |
| SCHEMBL3780486 | 0.74 | ALDH1A1 (0.32) | HTTALDH1A1 | |
| SCHEMBL11016745 | 0.71 | FLT1 (0.32) | KDM4EHSD17B10TSHR | |
| SCHEMBL29726936 | 0.71 | IDO1 (0.41) | MAPTCA12CA4CA7CA9 | |
| SCHEMBL1880902 | 0.71 | IDO1 (0.41) | MAPTCA12CA4CA7CA9 | |
| SCHEMBL6201094 | 0.69 | MAPT (0.52) | MAPTHTTCA12CA4CA7 | |
| SCHEMBL76608 | 0.69 | MAPT (1.00) | MAPTHTTHTR1AADRA1DADRA1A | |
| SCHEMBL29379717 | 0.69 | MAPT (1.00) | MAPTHTTHTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10324689-A | — | — | None | — | — | JP | disclosed |
| JP-H10324689-A | SILICON-CONTAINING ALFA-DIIMINE COMPOUND | SHIN ETSU CHEM CO LTD | 1998-12-08 | — | — | JP | disclosed |