Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103069 | 0.93 | TDP2 (0.59) | TDP2PAX8HKDC1TLR9MAPT | |
| SCHEMBL8665616 | 0.88 | MAPT (0.54) | TDP2PAX8HKDC1TLR9MAPT | |
| SCHEMBL8669699 | 0.86 | TDP2 (0.53) | TDP2PAX8HKDC1TLR9MAPT | |
| SCHEMBL8664901 | 0.86 | TDP2 (0.50) | TDP2PAX8HKDC1TLR9MAPT | |
| SCHEMBL8092511 | 0.85 | TDP2 (0.57) | TDP2PAX8HKDC1TLR9MAPT | |
| SCHEMBL8666088 | 0.84 | HSP90AA1 (0.51) | TDP2PAX8HKDC1TLR9MAPT | |
| SCHEMBL8102275 | 0.84 | TDP2 (0.56) | TDP2PAX8HKDC1TLR9MAPT | |
| SCHEMBL8669717 | 0.83 | MAPT (0.40) | TDP2PAX8HKDC1TLR9MAPT | |
| SCHEMBL8667425 | 0.80 | TDP2 (0.52) | TDP2PAX8HKDC1TLR9MAPT | |
| SCHEMBL8667530 | 0.80 | TDP2 (0.51) | TDP2PAX8HKDC1TLR9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882706-A1 | Cell adhesion inhibitors | ELI LILLY AND COMPANY (US) | 1998-12-09 | — | — | EP | disclosed |