Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 18/20 | 0.36 |
| ▸ | RARB | P10826 | 16/20 | 0.36 |
| ▸ | RARG | P13631 | 15/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.36 |
| ▸ | HNF4A | P41235 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664382 | 0.85 | RARB (0.44) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8682496 | 0.80 | RARA (0.46) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8682491 | 0.80 | RARA (0.46) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6292935 | 0.80 | PDK2 (0.45) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6818882 | 0.79 | RARB (0.48) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8981637 | 0.77 | RARA (0.60) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6238706 | 0.77 | RARA (0.60) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6238701 | 0.77 | RARA (0.60) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL7800461 | 0.77 | RARB (0.61) | RARARARBRARG | |
| SCHEMBL8331013 | 0.76 | RARB (0.59) | RARARARBRARGRXRANR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849923-A | Heterocyclic-substituted naphthalenyl retinobenzoic acid derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-12-15 | — | — | US | disclosed |