Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.63 |
| ▸ | CES1 | P23141 | 3/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666745 | 1.00 | CES2 (0.63) | CES2CES1GAAALDH1A1ALOX15 | |
| SCHEMBL27807409 | 0.79 | CES2 (0.74) | CES2CES1GAAALDH1A1ALOX15 | |
| SCHEMBL2156696 | 0.79 | CES2 (1.00) | CES2CES1GAAALDH1A1ALOX15 | |
| SCHEMBL8664565 | 0.78 | CES2 (0.43) | CES2CES1GAAALDH1A1ALOX15 | |
| SCHEMBL11526244 | 0.78 | SMN1; SMN2 (0.43) | ALDH1A1NPC1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL11526246 | 0.78 | SMN1; SMN2 (0.43) | ALDH1A1NPC1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL8664564 | 0.78 | CES2 (0.43) | CES2CES1GAAALDH1A1ALOX15 | |
| SCHEMBL6701425 | 0.78 | CES2 (0.66) | CES2CES1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL6701419 | 0.78 | CES2 (0.66) | CES2CES1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL10816398 | 0.77 | CES2 (0.63) | CES2CES1ALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786374-A | FUNGICIDES, MICROBIOCIDES | NOVARTIS CORPORATION (US) | 1998-07-28 | — | — | US | disclosed |
| EP-0789692-A1 | BENZISOXAZOLE DERIVATIVES AND PESTICIDAL COMPOSITIONS CONTAINING THEM | Novartis AG (CH) | 1997-08-20 | — | — | EP | disclosed |
| WO-1996014305-A1 | BENZISOXAZOLE DERIVATIVES AND PESTICIDAL COMPOSITIONS CONTAINING THEM | NOVARTIS AG (CH) | 1996-05-17 | — | — | WO | disclosed |