Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.37 |
| ▸ | LIPE | Q05469 | 2/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | CTSE | P14091 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669066 | 0.89 | PDE4D (0.38) | TP53USP30PDE4DGPR119LIPE | |
| SCHEMBL8668453 | 0.84 | GPR119 (0.39) | TP53PDE4DGPR119CTSDCTSE | |
| SCHEMBL9030280 | 0.66 | TP53 (0.51) | TP53PDE4DGPR119 | |
| SCHEMBL27189242 | 0.62 | TP53 (0.59) | TP53USP30GPR119CTSDCTSE | |
| SCHEMBL13335340 | 0.62 | GPR119 (0.70) | GPR119 | |
| SCHEMBL3756538 | 0.61 | GPR119 (0.52) | TP53USP30GPR119LMNA | |
| SCHEMBL3756543 | 0.61 | GPR119 (0.52) | TP53USP30GPR119LMNA | |
| SCHEMBL31441564 | 0.61 | TP53 (0.48) | TP53USP30GPR119CTSDCTSE | |
| SCHEMBL31441589 | 0.61 | TP53 (0.48) | TP53USP30GPR119CTSDCTSE | |
| SCHEMBL15019525 | 0.61 | HRH3 (0.55) | GPR119ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814636-A | TREATMENT AND PROPHYLAXIS OF THROMBOTIC DISEASES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1998-09-29 | — | — | US | disclosed |