SCHEMBL8666835

SCHEMBL8666835

CC(=O)C[C@@](O)(OC1[C@@H](C)O[C@H](c2ccccc2Cl)c2cc(Cl)ccc2N1CC(C)(C)C)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FDFT1 P37268 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6961349 0.84
SCHEMBL6964047 0.84
SCHEMBL6958522 0.84
SCHEMBL6951787 0.84
SCHEMBL6958094 0.76
SCHEMBL6959211 0.75 FDFT1 (0.36) FDFT1
SCHEMBL6963838 0.75 FDFT1 (0.36) FDFT1
SCHEMBL9057372 0.75 ALDH1A1 (0.37)
SCHEMBL7244925 0.73
SCHEMBL9057211 0.70 ALDH1A1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5726306-A INHIBITORS OF SQUALENE SYNTHETASE AND FUNGAL GROWTH; USEFUL IN TREATING AND PREVENTING HYPERLIPIDEMIA TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-03-10 US disclosed