Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 19/20 | 0.44 |
| ▸ | RARA | P10276 | 18/20 | 0.44 |
| ▸ | RARG | P13631 | 17/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667415 | 0.85 | RARB (0.45) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8666345 | 0.85 | RARB (0.62) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8661089 | 0.84 | RARB (0.50) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8664218 | 0.82 | RARB (0.46) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8661419 | 0.81 | RARB (0.48) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8661314 | 0.81 | RARB (0.47) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8331013 | 0.81 | RARB (0.59) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8664492 | 0.79 | RARB (0.65) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8665970 | 0.79 | RARA (0.46) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL7049910 | 0.78 | RARA (0.52) | RARBRARARARGRXRANR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849923-A | Heterocyclic-substituted naphthalenyl retinobenzoic acid derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-12-15 | — | — | US | claimed |
| US-5849923-A | Heterocyclic-substituted naphthalenyl retinobenzoic acid derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-12-15 | — | — | US | disclosed |