Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3031415 | 0.74 | APP (0.55) | APPMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18105076 | 0.74 | APP (0.55) | APPMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19062293 | 0.74 | APP (0.55) | APPMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8728146 | 0.74 | APP (0.55) | APPMAPTCYP1A2CYP3A4CYP2C9 | |
| Diphenylacetylene SCHEMBL29188592 | 0.73 | APP (1.00) | APPMAPTCYP1A2CYP3A4CYP2C9 | |
| Diphenylacetylene SCHEMBL960609 | 0.73 | APP (1.00) | APPMAPTCYP1A2CYP3A4CYP2C9 | |
| Diphenylacetylene SCHEMBL68254 | 0.73 | APP (1.00) | APPMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14300755 | 0.72 | APP (0.52) | APPMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4730312 | 0.72 | HTR2A (0.57) | APPMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13053106 | 0.70 | APP (0.67) | APPMAPTCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617073-B1 | Poly(silyleneethynylene phenyleneethynylenes), method for preparing same and hardened product thereof | MITSUI CHEMICALS INC (JP) | 1998-12-09 | — | — | EP | disclosed |
| US-5420238-A | Heat resistant | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0617073-A2 | Poly(silyleneethynylene phenyleneethynylenes), method for preparing same and hardened product thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1994-09-28 | — | — | EP | disclosed |