Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28377502 | 0.90 | ALDH1A1 (0.38) | ALDH1A1LMNAHPGDHTTGAA | |
| SCHEMBL8378760 | 0.86 | ALDH1A1 (0.40) | ALDH1A1LMNAGAAKMT2ACYP3A4 | |
| SCHEMBL22609672 | 0.83 | ALDH1A1 (0.37) | ALDH1A1LMNAHPGDGAAKMT2A | |
| SCHEMBL28796788 | 0.81 | ALDH1A1 (0.40) | ALDH1A1LMNAHPGDHTTGAA | |
| SCHEMBL19565191 | 0.80 | ALDH1A1 (0.40) | ALDH1A1LMNAHPGDHTTGAA | |
| SCHEMBL14595218 | 0.79 | ALDH1A1 (0.35) | ALDH1A1LMNAHPGDHTTGAA | |
| SCHEMBL1192851 | 0.79 | ALDH1A1 (0.44) | ALDH1A1LMNAHPGDHTTGAA | |
| SCHEMBL890842 | 0.79 | GAA (0.45) | ALDH1A1GAAKMT2ACYP3A4CYP2C9 | |
| SCHEMBL16384714 | 0.78 | ALDH1A1 (0.37) | ALDH1A1LMNAHPGDHTTGAA | |
| SCHEMBL11729140 | 0.78 | MCHR1 (0.43) | ALDH1A1LMNAHTTTSHRCYP24A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780403-A | Ash-free detergents their preparation and use in lubricating oil compositions | BP CHEMICALS (ADDITIVES) LIMITED (GB) | 1998-07-14 | — | — | US | disclosed |