Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD5 | P21918 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484680 | 0.98 | POLB (0.32) | POLB | |
| SCHEMBL8666560 | 0.80 | POLB (0.33) | POLB | |
| SCHEMBL8668056 | 0.80 | KDM2B (0.34) | POLB | |
| SCHEMBL8663542 | 0.80 | POLB (0.34) | POLB | |
| SCHEMBL8662771 | 0.79 | TSHR (0.33) | — | |
| SCHEMBL8676080 | 0.78 | POLB (0.33) | POLB | |
| SCHEMBL8343961 | 0.78 | HCRTR2 (0.34) | POLB | |
| SCHEMBL8479120 | 0.78 | POLB (0.34) | POLB | |
| SCHEMBL8655496 | 0.78 | POLB (0.33) | POLB | |
| SCHEMBL8481557 | 0.77 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |