Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CCR3 | P51677 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8481557 | 0.98 | TSHR (0.31) | TSHRSCN1ASCN2ASCN3AALDH1A1 | |
| SCHEMBL8665948 | 0.87 | PGR (0.31) | — | |
| SCHEMBL8486153 | 0.85 | — | — | |
| SCHEMBL8668056 | 0.80 | KDM2B (0.34) | CCR3 | |
| SCHEMBL8343961 | 0.80 | HCRTR2 (0.34) | — | |
| SCHEMBL8667893 | 0.79 | POLB (0.32) | — | |
| SCHEMBL8655496 | 0.78 | POLB (0.33) | HCRTR1 | |
| SCHEMBL8484680 | 0.77 | POLB (0.32) | TSHRALDH1A1 | |
| SCHEMBL8653115 | 0.77 | CCR3 (0.43) | TSHRALDH1A1CCR3 | |
| SCHEMBL8665513 | 0.76 | HCRTR1 (0.33) | HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |