Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665130 | 0.73 | ALDH1A1 (0.50) | HTR5AALDH1A1L3MBTL1DAOKDM4E | |
| SCHEMBL10333919 | 0.66 | NPC1 (0.48) | ALDH1A1L3MBTL1DAOKDM4EHTT | |
| SCHEMBL30003476 | 0.63 | TSHR (0.55) | ALDH1A1L3MBTL1DAOKDM4EHTT | |
| SCHEMBL1154872 | 0.63 | TSHR (0.55) | ALDH1A1L3MBTL1DAOKDM4EHTT | |
| SCHEMBL643810 | 0.63 | KDM4E (0.54) | HTR5AALDH1A1L3MBTL1DAOKDM4E | |
| SCHEMBL1703105 | 0.62 | KDM4E (0.48) | HTR5AALDH1A1L3MBTL1DAOKDM4E | |
| Hydrochloric Acid SCHEMBL27297244 | 0.62 | TSHR (0.53) | ALDH1A1L3MBTL1DAOKDM4EHTT | |
| SCHEMBL8172779 | 0.62 | KDM4E (0.52) | HTR5AALDH1A1L3MBTL1DAOKDM4E | |
| SCHEMBL1360579 | 0.62 | TSHR (0.53) | ALDH1A1L3MBTL1DAOKDM4EHTT | |
| Hno SCHEMBL28954421 | 0.60 | KDM4E (0.50) | HTR5AALDH1A1L3MBTL1DAOKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750552-A | ANTIULCER AGENTS | ARAX CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0736527-A1 | Imadazoline derivative, possible tautomer thereof, process of manufacturing therefor, and vulnerary including such derivative or tautomer | ARAX CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |