Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5729337 | 0.66 | KMT2A (0.43) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL22782149 | 0.65 | NPC1 (0.54) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL3703843 | 0.61 | NPC1 (0.51) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL3022267 | 0.61 | KMT2A (0.51) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL11706723 | 0.59 | NPC1 (0.49) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL5729334 | 0.57 | NPC1 (0.46) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL1255973 | 0.56 | — | — | |
| SCHEMBL11770529 | 0.56 | RAB9A (1.00) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL564859 | 0.56 | NPC1 (0.37) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL18537415 | 0.55 | NPC1 (0.41) | NPC1RAB9AKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876332-A1 | PHENYLACETIC ACID DERIVATIVES, PROCESS AND INTERMEDIATE PRODUCTS FOR USE IN PRODUCING THEM AND AGENTS CONTAINING THEM | BASF AKTIENGESELLSCHAFT (DE) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997015552-A1 | PHENYLACETIC ACID DERIVATIVES, PROCESS AND INTERMEDIATE PRODUCTS FOR USE IN PRODUCING THEM AND AGENTS CONTAINING THEM | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-01 | — | — | WO | disclosed |
| US-5536734-A | FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1996-07-16 | — | — | US | disclosed |