Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.66 |
| ▸ | BCHE | P06276 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23945258 | 0.90 | TDP1 (0.70) | TDP1KMT2ASLC6A2SLC6A3BCHE | |
| SCHEMBL1446744 | 0.88 | TDP1 (0.68) | TDP1KMT2ASLC6A2SLC6A3BCHE | |
| SCHEMBL1674740 | 0.88 | TDP1 (0.88) | TDP1KMT2ASLC6A2SLC6A3BCHE | |
| SCHEMBL20083912 | 0.86 | NPC1 (0.67) | TDP1KMT2ASLC6A2SLC6A3BCHE | |
| SCHEMBL11985698 | 0.86 | TDP1 (0.76) | TDP1KMT2ASLC6A2SLC6A3BCHE | |
| SCHEMBL223441 | 0.86 | TDP1 (1.00) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL26190081 | 0.85 | TDP1 (0.54) | TDP1KMT2ASLC6A2SLC6A3BCHE | |
| SCHEMBL22832400 | 0.84 | TDP1 (0.81) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL115000 | 0.84 | TDP1 (0.81) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL11985735 | 0.84 | TDP1 (0.73) | TDP1KMT2ASLC6A2SLC6A3BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5833880-A | MIXTURE POLYMERIZABLE BY FREE RADICAL OR IONIC POLYMERIZATION | BASF AKTIENGESELLSCHAFT (DE) | 1998-11-10 | — | — | US | disclosed |