Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.70 |
| ▸ | ESR1 | P03372 | 1/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1446744 | 0.98 | TDP1 (0.68) | TDP1KMT2ASLC6A2SLC6A3ESR1 | |
| SCHEMBL27926522 | 0.92 | TDP1 (0.59) | TDP1KMT2ASLC6A2SLC6A3ESR1 | |
| SCHEMBL17955287 | 0.91 | L3MBTL1 (0.58) | TDP1KMT2ASLC6A2SLC6A3ESR1 | |
| SCHEMBL16594029 | 0.90 | L3MBTL1 (0.56) | TDP1KMT2ASLC6A2SLC6A3ESR1 | |
| SCHEMBL8668089 | 0.90 | TDP1 (0.73) | TDP1KMT2ASLC6A2SLC6A3ESR1 | |
| SCHEMBL16320579 | 0.88 | ESR1 (0.70) | TDP1KMT2ASLC6A2SLC6A3ESR1 | |
| SCHEMBL15512622 | 0.87 | TDP1 (0.73) | TDP1KMT2ASLC6A2SLC6A3ESR1 | |
| SCHEMBL15512201 | 0.87 | TDP1 (0.73) | TDP1KMT2ASLC6A2SLC6A3ESR1 | |
| SCHEMBL15512282 | 0.87 | TDP1 (0.73) | TDP1KMT2ASLC6A2SLC6A3ESR1 | |
| SCHEMBL205788 | 0.87 | TDP1 (0.73) | TDP1KMT2ASLC6A2SLC6A3ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021211423-A1 | METHODS FOR DEPOLYMERIZING POLYESTERS | NORTHWESTERN UNIVERSITY (US) | 2021-10-21 | — | — | WO | disclosed |