Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.59 |
| ▸ | ACE | P12821 | 2/20 | 0.59 |
| ▸ | CPA1 | P15085 | 1/20 | 0.59 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.59 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3660997 | 1.00 | MME (0.59) | MMEACECPA1ACE2HRH4 | |
| SCHEMBL3658383 | 0.96 | MME (0.58) | MMEACECPA1ACE2HRH4 | |
| SCHEMBL8673998 | 0.96 | MME (0.58) | MMEACECPA1ACE2HRH4 | |
| SCHEMBL3658631 | 0.95 | FAAH (0.58) | MMEACECPA1ACE2HRH4 | |
| SCHEMBL21772500 | 0.95 | FAAH (0.58) | MMEACECPA1ACE2HRH4 | |
| SCHEMBL3658643 | 0.95 | FAAH (0.58) | MMEACECPA1ACE2HRH4 | |
| SCHEMBL3662267 | 0.95 | FAAH (0.58) | MMEACECPA1ACE2HRH4 | |
| SCHEMBL3660631 | 0.95 | FAAH (0.58) | MMEACECPA1ACE2HRH4 | |
| SCHEMBL3663736 | 0.95 | FAAH (0.58) | MMEACECPA1ACE2HRH4 | |
| SCHEMBL3660699 | 0.95 | FAAH (0.58) | MMEACECPA1ACE2HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849781-A | Tricyclic amides | ADIR ET COMPAGNIE (FR) | 1998-12-15 | — | — | US | disclosed |
| US-5712312-A | MELATONINERGIC RECEPTOR LIGANDS, TREATMENT OF SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1998-01-27 | — | — | US | disclosed |