SCHEMBL8668263

SCHEMBL8668263

CN1C2CCC1C(CCC(=O)O)C(OC(=O)c1ccccc1)C2

nearest known ligand 0.77

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.63
CHRM4 P08173 1/20 0.63
CHRM1 P11229 1/20 0.63
CHRM3 P20309 1/20 0.63
KCNH2 Q12809 2/20 0.62
MAPT P10636 1/20 0.62
MAOA P21397 1/20 0.62
SLC6A2 P23975 1/20 0.62
SLC6A4 P31645 1/20 0.62
SCN1A P35498 1/20 0.62
SLC6A3 Q01959 1/20 0.62
SCN2A Q99250 1/20 0.62
SIGMAR1 Q99720 1/20 0.62
SCN3A Q9NY46 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3021898 0.87 CHRM2 (0.67) CHRM2CHRM4CHRM1CHRM3KCNH2
SCHEMBL3021901 0.87 CHRM2 (0.67) CHRM2CHRM4CHRM1CHRM3KCNH2
Theracys SCHEMBL367470 0.80 KCNH2 (0.80) KCNH2MAPTMAOASLC6A2SLC6A4
Theracys SCHEMBL328885 0.80 KCNH2 (0.80) KCNH2MAPTMAOASLC6A2SLC6A4
Theracys SCHEMBL328884 0.80 KCNH2 (0.80) KCNH2MAPTMAOASLC6A2SLC6A4
Theracys SCHEMBL13196454 0.80 KCNH2 (0.80) KCNH2MAPTMAOASLC6A2SLC6A4
Theracys SCHEMBL18648964 0.80 KCNH2 (0.80) KCNH2MAPTMAOASLC6A2SLC6A4
Theracys SCHEMBL116803 0.80 KCNH2 (0.80) KCNH2MAPTMAOASLC6A2SLC6A4
Theracys SCHEMBL16922152 0.80 KCNH2 (0.80) KCNH2MAPTMAOASLC6A2SLC6A4
SCHEMBL13318704 0.79 KCNH2 (0.78) KCNH2MAPTMAOASLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5817770-A N-METHYLTROPANE, 2-CARBOXYETHYL- OR N-ETHYLCARBOXAMIDE, 3-BENZOYLOXY- OR BENZAMIDO- DRUG ABUSE SCIENCES, INC. (US) 1998-10-06 US claimed