Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21993827 | 0.82 | TSHR (0.52) | KMT2AL3MBTL1TSHR | |
| SCHEMBL12643708 | 0.82 | TSHR (0.52) | KMT2AL3MBTL1TSHR | |
| SCHEMBL8670246 | 0.82 | CYP2C19 (0.41) | KMT2ATSHRCYP2C19 | |
| SCHEMBL27742382 | 0.81 | KLK7 (0.41) | KMT2ARECQLTSHRCYP2C19 | |
| SCHEMBL8899635 | 0.74 | RECQL (0.40) | RECQLTSHRABCB1CYP2C19KDM1A | |
| SCHEMBL14649976 | 0.71 | FABP5 (0.41) | KMT2AL3MBTL1RECQLKDM1AMAOB | |
| SCHEMBL19428590 | 0.71 | FABP5 (0.41) | KMT2AL3MBTL1RECQLKDM1AMAOB | |
| SCHEMBL10326487 | 0.71 | RECQL (0.46) | KMT2ARECQLTSHRABCB1KDM1A | |
| SCHEMBL27742379 | 0.71 | KLK7 (0.42) | KMT2AL3MBTL1TSHR | |
| SCHEMBL8695989 | 0.70 | KCNH2 (0.50) | RECQLABCB1CYP2C19KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707991-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE | RHONE-POULENC RORER S.A. (FR) | 1998-01-13 | — | — | US | disclosed |