Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10326768 | 0.81 | CYP2D6 (0.54) | LMNATDP1CYP2D6SMN1; SMN2ALDH1A1 | |
| SCHEMBL8899635 | 0.75 | RECQL (0.40) | RECQLCHRNA7ABCB1LMNACYP2D6 | |
| SCHEMBL5450650 | 0.74 | CYP2D6 (0.40) | RECQLCHRNA7ABCB1LMNATDP1 | |
| SCHEMBL3009817 | 0.74 | SMN1; SMN2 (0.47) | CHRNA7LMNATDP1SMN1; SMN2MEN1 | |
| SCHEMBL5531847 | 0.74 | SMN1; SMN2 (0.47) | CHRNA7LMNATDP1SMN1; SMN2MEN1 | |
| SCHEMBL7080229 | 0.74 | SMN1; SMN2 (0.47) | CHRNA7LMNATDP1SMN1; SMN2MEN1 | |
| SCHEMBL8695989 | 0.72 | KCNH2 (0.50) | RECQLABCB1KDM1AMAOB | |
| SCHEMBL8695987 | 0.72 | KCNH2 (0.50) | RECQLABCB1KDM1AMAOB | |
| SCHEMBL8668385 | 0.71 | KMT2A (0.38) | RECQLABCB1KDM1AMAOBKMT2A | |
| SCHEMBL9488854 | 0.71 | TSHR (0.61) | RECQLABCB1TDP1KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217204-B2 | Catalyst for asymmetric hydrogenation | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2012-07-10 | — | — | US | disclosed |
| US-20100324338-A1 | CATALYST FOR ASYMMETRIC HYDROGENATION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324338-A1 | CATALYST FOR ASYMMETRIC HYDROGENATION | H1-0, H1-5, ADH5 | RECQL 4078/4885CHRNA7 1388/4885ABCB1 4856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.