Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10643820 | 0.84 | HSD17B10 (0.46) | SMN1; SMN2MAPTLMNAHPGDPDE4D | |
| SCHEMBL80422 | 0.83 | TDP1 (0.49) | MAPTLMNATDP1HPGDALDH1A1 | |
| SCHEMBL30254595 | 0.83 | TDP1 (0.49) | MAPTLMNATDP1HPGDALDH1A1 | |
| SCHEMBL8666383 | 0.82 | TDP1 (0.47) | SMN1; SMN2MAPTLMNAMITFHTT | |
| SCHEMBL490715 | 0.73 | AKR1C3 (0.46) | SMN1; SMN2MAPTHTTALDH1A1MAPK1 | |
| SCHEMBL2137404 | 0.72 | ALDH1A1 (0.63) | SMN1; SMN2MAPTLMNAMITFHTT | |
| Water SCHEMBL27408458 | 0.70 | ALDH1A1 (0.61) | SMN1; SMN2MAPTLMNAMITFHTT | |
| SCHEMBL490742 | 0.69 | NPC1 (0.53) | SMN1; SMN2MAPTLMNATDP1ALDH1A1 | |
| Formaldehyde SCHEMBL29219144 | 0.69 | ALDH1A1 (0.59) | SMN1; SMN2MAPTLMNAMITFHTT | |
| SCHEMBL10904251 | 0.68 | ALDH1A1 (0.63) | SMN1; SMN2LMNATDP1HPGDCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792589-A | ORGANIC BINDER; OPTICALLY CROSSLINKABLE COMPOUND; RADICAL-GENERATING AGENT: 2,4,5-TRIARYL IMIDAZOLE DIMER, AMINO-GROUP CONTAINING BENZOPHENONE PHOTOSENSITIZER, A THIOL COMPOUND | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1998-08-11 | — | — | US | disclosed |