SCHEMBL8668623

SCHEMBL8668623

C=C(C)C(=O)OC(CC)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.34
THRB P10828 1/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL673328 0.94 TSHR (0.33) TSHRTHRBALDH1A1
SCHEMBL2529851 0.94 TSHR (0.33) TSHRTHRBALDH1A1
SCHEMBL17297569 0.84 TSHR (0.40) TSHRALDH1A1
SCHEMBL8375972 0.82 TSHR (0.38) TSHRTHRBALDH1A1
SCHEMBL5523582 0.82 TSHR (0.33) TSHRALDH1A1
SCHEMBL751392 0.81 ALDH1A1 (0.32) TSHRALDH1A1
SCHEMBL74906 0.81 TSHR (0.35) TSHRTHRBALDH1A1
SCHEMBL12856941 0.81 TSHR (0.37) TSHRTHRBALDH1A1
SCHEMBL2452427 0.81 TSHR (0.33) TSHRALDH1A1
SCHEMBL9610662 0.80 TSHR (0.34) TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0665252-B1 Two-pack aqueous coating composition KANSAI PAINT CO LTD (JP) 1998-12-16 EP disclosed
US-5519089-A ALKOXYSILANE CONTAINING ACRYLIC COPOLYMER AND POLYISOCYANATE KANSAI PAINT CO., LTD. (JP) 1996-05-21 US disclosed
EP-0665252-A2 Two-pack aqueous coating composition KANSAI PAINT CO., LTD. (JP) 1995-08-02 EP disclosed
US-4812337-A METALLIC PIGMENT BASE COAT, CLEAR TOP COAT KANSAI PAINT COMPANY, LIMITED (JP) 1989-03-14 US disclosed
US-4732941-A POLYMER ADDED AS STABILIZER KANSAI PAINT COMPANY, LIMITED (JP) 1988-03-22 US disclosed