Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757447 | 0.77 | HSPA5 (0.50) | TAAR1HPGDALDH1A1TSHRCA2 | |
| SCHEMBL1612108 | 0.77 | TAAR1 (0.43) | TAAR1HPGDALDH1A1CTBP2CHRM2 | |
| SCHEMBL8668744 | 0.76 | TAAR1 (0.39) | TAAR1HPGDALDH1A1CTBP2CHRM2 | |
| SCHEMBL11687737 | 0.76 | TAAR1 (0.46) | TAAR1HPGDALDH1A1CTBP2CHRM2 | |
| SCHEMBL28772084 | 0.73 | CYP1A2 (0.47) | TAAR1HPGDALDH1A1KMT2AHTT | |
| SCHEMBL3338 | 0.72 | — | — | |
| SCHEMBL29928074 | 0.72 | — | — | |
| SCHEMBL367154 | 0.72 | TDP1 (0.47) | HPGDHTT | |
| SCHEMBL3645165 | 0.71 | TAAR1 (0.46) | TAAR1HPGDALDH1A1CTBP2CHRM2 | |
| SCHEMBL102904 | 0.71 | ALDH1A1 (0.47) | TAAR1HPGDALDH1A1CTBP2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753649-A | Therapeutic agent for osteoporosis and diazepine compound | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5593988-A | DIAZIPINE DERIVATIVES OF THIOPHENE FOR BONE DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0638560-A1 | REMEDY FOR OSTEOPOROSIS AND DIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |