SCHEMBL8668950

SCHEMBL8668950

Cc1cc(C)c2c(c1)-c1ccccc1C2=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.53
TTR P02766 2/20 0.53
KMT2A Q03164 8/20 0.46
MEN1 O00255 7/20 0.46
MAPT P10636 6/20 0.46
MAPK1 P28482 4/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
KDM4E B2RXH2 4/20 0.46
POLB P06746 3/20 0.46
RECQL P46063 3/20 0.46
MAOA P21397 3/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
THRB P10828 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
LMNA P02545 2/20 0.46
CES2 O00748 1/20 0.46
APAF1 O14727 1/20 0.46
TERT O14746 1/20 0.46
PLIN1 O60240 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL985103 0.92 TTR (0.62) ELANETTRKMT2AMEN1MAPT
SCHEMBL31484750 0.85 TTR (0.47) ELANETTRKMT2AMEN1MAPT
SCHEMBL8771223 0.84 ELANE (0.53) ELANETTRKMT2AMEN1MAPT
SCHEMBL12460172 0.84 ELANE (0.59) ELANETTRKMT2AMEN1MAPT
SCHEMBL6904482 0.83 ELANE (0.45) ELANETTRKMT2AMEN1MAPT
SCHEMBL3979103 0.82 ELANE (0.49) ELANETTRKMT2AMEN1MAPT
SCHEMBL11077084 0.81 MAPT (0.65) ELANETTRKMT2AMEN1MAPT
SCHEMBL31379951 0.78 ELANE (0.62) ELANETTRKMT2AMEN1MAPT
SCHEMBL6905738 0.78 ELANE (0.62) ELANETTRKMT2AMEN1MAPT
SCHEMBL13168815 0.78 MAPT (0.56) ELANETTRKMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113652705-B Method for synthesizing fluorenone through catalytic electrolysis of N-hydroxyphthalimide 北京工业大学 2022-07-22 CN disclosed
CN-113652705-A Method for synthesizing fluorenone by catalyzing and electrolyzing N-hydroxyphthalimide 北京工业大学 2021-11-16 CN disclosed
EP-0886182-A1 Positive photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-12-23 EP disclosed