Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | ELANE | P08246 | 4/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.65 |
| ▸ | RECQL | P46063 | 2/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | BCL2 | P10415 | 2/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.58 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.56 |
| ▸ | PIM1 | P11309 | 3/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pachybasin SCHEMBL7624909 | 0.93 | MAPT (0.75) | MAPTMEN1KMT2AALDH1A1ELANE | |
| Pachybasin SCHEMBL31536859 | 0.93 | MAPT (0.75) | MAPTMEN1KMT2AALDH1A1ELANE | |
| SCHEMBL11080514 | 0.85 | LCK (0.68) | MAPTMEN1KMT2AALDH1A1ELANE | |
| SCHEMBL19461856 | 0.84 | ALDH1A1 (0.90) | MAPTMEN1KMT2AALDH1A1ELANE | |
| Chrysophanol SCHEMBL9879838 | 0.83 | ALDH1A1 (0.94) | MAPTMEN1KMT2AALDH1A1ELANE | |
| SCHEMBL8668950 | 0.81 | ELANE (0.53) | MAPTMEN1KMT2AALDH1A1ELANE | |
| SCHEMBL11083159 | 0.79 | MCL1 (0.59) | MAPTMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL9170655 | 0.79 | MAPT (0.72) | MAPTMEN1KMT2AALDH1A1ELANE | |
| SCHEMBL29359680 | 0.79 | MAPT (0.72) | MAPTMEN1KMT2AALDH1A1ELANE | |
| Chrysophanol SCHEMBL308131 | 0.79 | ALDH1A1 (1.00) | MAPTMEN1KMT2AALDH1A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447420-A | Fluorenone esters of phosphoric and phosphonic acids as insecticides | VELSICOL CHEMICAL CORPORATION (US) | 1984-05-08 | — | — | US | disclosed |