Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | APEX1 | P27695 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12618074 | 0.91 | POLB (0.56) | ALDH1A1APEX1TDP1LMNAPOLB | |
| SCHEMBL11997926 | 0.87 | POLB (0.52) | ALDH1A1APEX1TDP1POLBHTT | |
| SCHEMBL14142193 | 0.86 | APEX1 (0.58) | ALDH1A1APEX1TDP1LMNAALOX15 | |
| SCHEMBL12376906 | 0.85 | POLB (0.50) | ALDH1A1APEX1TDP1LMNAPOLB | |
| SCHEMBL9018658 | 0.83 | TDP1 (0.64) | ALDH1A1APEX1TDP1LMNAALOX15 | |
| SCHEMBL59813 | 0.83 | POLB (0.56) | ALDH1A1APEX1TDP1LMNAPOLB | |
| SCHEMBL2831138 | 0.83 | POLB (0.56) | ALDH1A1APEX1TDP1POLBHTT | |
| SCHEMBL14173142 | 0.83 | POLB (0.56) | ALDH1A1APEX1TDP1LMNAPOLB | |
| SCHEMBL454606 | 0.81 | POLB (0.67) | ALDH1A1APEX1TDP1LMNAPOLB | |
| SCHEMBL13923791 | 0.80 | TDP1 (0.60) | ALDH1A1APEX1TDP1LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10081716-A | — | — | None | — | — | JP | disclosed |
| JP-9169699-A | — | — | None | — | — | JP | disclosed |
| JP-H1081716-A | ULTRAVIOLET RAY ABSORBING AGENT | OSAKA ORGANIC CHEM IND LTD | 1998-03-31 | — | — | JP | disclosed |
| JP-H09169699-A | NEW DIBENZOYLMETHANE DERIVATIVE AND ITS PRODUCTION | OSAKA ORGANIC CHEM IND LTD | 1997-06-30 | — | — | JP | disclosed |