Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CBX7 | O95931 | 1/20 | 0.38 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.38 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825252 | 0.83 | OPRM1 (0.42) | OPRM1OPRL1CNR1GPR55TP53 | |
| SCHEMBL7823775 | 0.78 | OPRM1 (0.44) | OPRM1OPRL1CNR1GPR55TP53 | |
| SCHEMBL7824852 | 0.75 | OPRM1 (0.41) | OPRM1OPRL1CNR1GPR55TP53 | |
| SCHEMBL26891305 | 0.75 | CNR1 (0.54) | CNR1GPR55POLBALDH1A1GAA | |
| SCHEMBL7014237 | 0.74 | TP53 (0.52) | OPRM1OPRL1CNR1GPR55TP53 | |
| SCHEMBL31559833 | 0.74 | TP53 (0.52) | OPRM1OPRL1CNR1GPR55TP53 | |
| SCHEMBL7824845 | 0.73 | OPRM1 (0.44) | OPRM1OPRL1CNR1GPR55TP53 | |
| SCHEMBL12659381 | 0.73 | KDM4E (0.47) | CNR1GPR55TP53THRBKDM4E | |
| SCHEMBL7836405 | 0.70 | SCN9A (0.48) | OPRM1OPRL1CNR1GPR55TP53 | |
| SCHEMBL7824666 | 0.68 | ITGB2 (0.54) | OPRM1OPRL1ALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773448-A | NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY LIMITED (GB) | 1998-06-30 | — | — | US | disclosed |