Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4366616 | 0.87 | CD274 (0.58) | LMNACD274SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8666812 | 0.84 | LMNA (0.46) | LMNAALDH1A1GAACD274L3MBTL1 | |
| SCHEMBL8770412 | 0.83 | SMN1; SMN2 (0.46) | LMNAALDH1A1KDM4ECD274L3MBTL1 | |
| SCHEMBL21338348 | 0.82 | LMNA (0.63) | LMNAGAAL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL5019074 | 0.81 | LMNA (0.73) | LMNAALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL4380661 | 0.80 | CHRM2 (0.60) | HTTRECQL | |
| SCHEMBL4203774 | 0.80 | CHRM2 (0.63) | MAPTSMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL14985738 | 0.80 | LMNA (0.63) | LMNAALDH1A1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL13365569 | 0.79 | LMNA (0.67) | LMNAGAAL3MBTL1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4506331 | 0.79 | LMNA (0.71) | LMNAALDH1A1GAAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5853699-A | Use of tetra azacycle complexes as x-ray diagnostic agents for the liver and gallbladder | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-12-29 | — | — | US | disclosed |