SCHEMBL8669442

SCHEMBL8669442

Oc1ccccc1N=Nc1nccs1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.67
KMT2A Q03164 9/20 0.67
MEN1 O00255 7/20 0.67
L3MBTL1 Q9Y468 4/20 0.67
KDM4E B2RXH2 4/20 0.67
NPSR1 Q6W5P4 3/20 0.67
TDP1 Q9NUW8 3/20 0.67
POLB P06746 2/20 0.67
MAPK1 P28482 2/20 0.67
IDO1 P14902 1/20 0.67
TDO2 P48775 1/20 0.67
GFER P55789 1/20 0.67
HSP90AA1 P07900 3/20 0.63
CCR6 P51684 1/20 0.63
RAB9A P51151 2/20 0.56
RIOK2 Q9BVS4 2/20 0.56
PAX8 Q06710 1/20 0.56
KCNH2 Q12809 1/20 0.56
SMN1; SMN2 Q16637 5/20 0.55
LMNA P02545 5/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8669440 1.00 MAPT (0.67) MAPTKMT2AMEN1L3MBTL1KDM4E
SCHEMBL3683056 0.81 KMT2A (0.66) MAPTKMT2AMEN1L3MBTL1KDM4E
SCHEMBL1683189 0.80 MAPT (1.00) MAPTKMT2AMEN1L3MBTL1KDM4E
SCHEMBL30875594 0.80 MAPT (1.00) MAPTKMT2AMEN1L3MBTL1KDM4E
SCHEMBL30491095 0.80 MAPT (1.00) MAPTKMT2AMEN1L3MBTL1KDM4E
SCHEMBL1683188 0.80 MAPT (1.00) MAPTKMT2AMEN1L3MBTL1KDM4E
SCHEMBL8743293 0.79 L3MBTL1 (0.55) MAPTKMT2AMEN1L3MBTL1KDM4E
SCHEMBL28012555 0.78 MAPT (0.65) MAPTKMT2AMEN1L3MBTL1KDM4E
SCHEMBL5728387 0.78 L3MBTL1 (1.00) MAPTKMT2AMEN1L3MBTL1KDM4E
SCHEMBL5728388 0.78 L3MBTL1 (1.00) MAPTKMT2AMEN1L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112540075-A Method and kit for detecting acid value of oil 月旭科技(上海)股份有限公司 2021-03-23 CN claimed
CN-112540075-A Method and kit for detecting acid value of oil 月旭科技(上海)股份有限公司 2021-03-23 CN disclosed
EP-0886183-A1 Positive-working photoresist composition Fuji Photo Film Co., Ltd. (JP) 1998-12-23 EP disclosed
US-5700620-A POSITIVE PHOTORESIST HAVING HIGH RESOLUTION AND SMALL FILM THICKNESS DEPENDENCE FUJI PHOTO FILM CO., LTD. (JP) 1997-12-23 US disclosed
US-5609982-A Positive-working photoresist composition FUJI PHOTO FILM CO., LTD. (JP) 1997-03-11 US disclosed
EP-0658807-A1 Positive-working photoresist composition FUJI PHOTO FILM CO., LTD. (JP) 1995-06-21 EP disclosed