⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL500442 | 0.91 | LMNA (0.30) | — | |
| SCHEMBL499822 | 0.88 | LMNA (0.35) | — | |
| SCHEMBL3026360 | 0.88 | LMNA (0.35) | — | |
| SCHEMBL3021662 | 0.88 | LMNA (0.35) | — | |
| SCHEMBL6652344 | 0.88 | LMNA (0.35) | — | |
| SCHEMBL6653004 | 0.88 | LMNA (0.35) | — | |
| SCHEMBL150892 | 0.88 | LMNA (0.35) | — | |
| SCHEMBL28207928 | 0.84 | LMNA (0.32) | — | |
| SCHEMBL2090356 | 0.82 | — | — | |
| SCHEMBL10453930 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346014-B1 | Therapeutic product for the treatment of peri- or postmenopausal conditions | ZENECA LTD (GB) | 1994-08-03 | — | — | EP | claimed |
| US-5183814-A | Administering estrogen and antiestrogen | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-02 | — | — | US | claimed |
| EP-0166509-B1 | PHENOL DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-05-13 | — | — | EP | claimed |
| US-5021414-A | Antiestrogen | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-04 | — | — | US | claimed |
| US-4904661-A | ANTIESTROGENS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-27 | — | — | US | claimed |
| EP-0346014-A1 | Therapeutic product for the treatment of peri- or postmenopausal conditions | ZENECA LIMITED (GB) | 1989-12-13 | — | — | EP | claimed |
| EP-0163416-B1 | PHENOL DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-05-31 | — | — | EP | claimed |
| EP-0160508-B1 | PHENOL DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-05-31 | — | — | EP | claimed |
| US-4833135-A | Antioestrogenic phenol derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-05-23 | — | — | US | claimed |
| US-4760061-A | Antioestrogenic agent | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-07-26 | — | — | US | claimed |
| US-4751240-A | ANTIFERTILITY AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-06-14 | — | — | US | claimed |
| US-4732912-A | ANTIESTROGENS, ANTITUMOR AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-22 | — | — | US | claimed |
| EP-0124369-B1 | PHENOL DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-06-24 | — | — | EP | claimed |
| EP-0166509-A1 | Phenol derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-01-02 | — | — | EP | claimed |
| EP-0163416-A2 | Phenol derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-12-04 | — | — | EP | claimed |
| EP-0160508-A2 | Phenol derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-11-06 | — | — | EP | claimed |
| EP-0124369-A1 | Phenol derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-07 | — | — | EP | claimed |
| US-11993578-B2 | Pyrazole-3-carboxylic acid amide derivative and pest control agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2024-05-28 | — | — | US | disclosed |
| US-4317616-A | Fluorosiloxane optical cladding | RAYCHEM CORPORATION (US) | 1982-03-02 | — | — | US | disclosed |
| EP-0027059-A1 | Optical waveguide | RAYCHEM CORPORATION (a California corporation) (US) | 1981-04-15 | — | — | EP | disclosed |