SCHEMBL8669520

SCHEMBL8669520

CC(=O)N(C)C.CCC(CC)C(N)=O

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.50
CA1 P00915 3/20 0.50
TSHR P16473 2/20 0.39
USP2 O75604 1/20 0.39
SLC1A3 P43003 1/20 0.35
SLC1A2 P43004 1/20 0.35
SLC1A1 P43005 1/20 0.35
MAPK1 P28482 1/20 0.32
LMNA P02545 1/20 0.32
ALOX15 P16050 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
HTT P42858 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CA7 P43166 1/20 0.30
CA14 Q9ULX7 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL28248012 0.85 CA2 (0.58) CA2CA1TSHRUSP2SLC1A3
SCHEMBL18737 0.84
SCHEMBL3178200 0.82
Hydrochloric Acid SCHEMBL530588 0.82
Dimethylformamide SCHEMBL17559887 0.79 CA2 (0.48) CA2CA1TSHRUSP2SLC1A3
Isobutyramide SCHEMBL8669513 0.77 CA2 (0.56) CA2CA1TSHRUSP2SLC1A3
Acetic Acid SCHEMBL28540051 0.76 CA2 (0.50) CA2CA1TSHRUSP2SLC1A3
SCHEMBL16773752 0.76 CA2 (0.50) CA2CA1TSHRUSP2SLC1A3
Phosphoric Acid SCHEMBL11347637 0.75 CA2 (0.54) CA2CA1TSHRUSP2SLC1A3
SCHEMBL22215230 0.74 CA1 (0.34) CA2CA1LMNAALOX15BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5851961-A Anti-settling lubricity agent for water/oil dispersion compositions THE LUBRIZOL CORPORATION (US) 1998-12-22 US disclosed
EP-0398505-B1 Metal carboxylate compositions and their use for reducing friction between relatively slideable components LUBRIZOL CORP (US) 1996-10-02 EP disclosed
US-5534169-A Methods for reducing friction between relatively slideable components using metal carboxylates THE LUBRIZOL CORPORATION (US) 1996-07-09 US disclosed
US-5213697-A Metal salt, organic liquid, surfactant THE LUBRIZOL CORPORATION (US) 1993-05-25 US disclosed
EP-0394033-B1 METHOD FOR REDUCING FRICTION BETWEEN RAILROAD WHEEL AND RAILWAY TRACK USING METAL OVERBASED COLLOIDAL DISPERSE SYSTEMS The Lubrizol Corporation (US) 1993-01-13 EP disclosed
EP-0398505-A1 Metal carboxylate compositions and their use for reducing friction between relatively slideable components The Lubrizol Corporation (US) 1990-11-22 EP disclosed
EP-0394033-A1 Method for reducing friction between railroad wheel and railway track using metal overbased colloidal disperse systems The Lubrizol Corporation (US) 1990-10-24 EP disclosed
EP-0084966-B1 AQUEOUS COMPOSITIONS CONTAINING OVERBASED MATERIALS The Lubrizol Corporation (US) 1989-11-08 EP disclosed
US-4629753-A POLYMER AND COLLOIDAL SYSTEM OF METAL SALTS, DISPERSANT, AND OVERBASED COMPOUND; AUTOMOBILE UNDERCOATINGS THE LUBRIZOL CORPORATION (US) 1986-12-16 US disclosed
EP-0094261-B1 ONE-COMPONENT MOISTURE CURABLE URETHANE COATING SYSTEM The Lubrizol Corporation (US) 1986-12-03 EP disclosed
US-4468339-A AND SOLUBILIZER WHICH IS REACTION OF CARBOXYLIC ACID ACYLATING AGENT WITH HYDROCARBON SUBSTITMENT AND HYDROXYAMINE THE LUBRIZOL CORPORATION (US) 1984-08-28 US disclosed
US-4443577-A COLLOIDAL DISPERSE SYSTEM, OVERBASED SALTS THE LUBRIZOL CORPORATION (US) 1984-04-17 US disclosed
EP-0094261-A2 One-component moisture curable urethane coating system The Lubrizol Corporation (US) 1983-11-16 EP disclosed
EP-0094196-A2 Two-component urethane coating system The Lubrizol Corporation (US) 1983-11-16 EP disclosed
EP-0084966-A2 Aqueous compositions containing overbased materials The Lubrizol Corporation (US) 1983-08-03 EP disclosed