SCHEMBL8669718

SCHEMBL8669718

COCC(C)OC(=O)C=CC(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 11/20 0.59
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
GAA P10253 1/20 0.35
TSHR P16473 2/20 0.35
TP53 P04637 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
EGLN3 Q9H6Z9 1/20 0.35
KEAP1 Q14145 1/20 0.34
NFE2L2 Q16236 1/20 0.34
GABRP O00591 2/20 0.33
GABRD O14764 2/20 0.33
GABRA1 P14867 2/20 0.33
GABRB1 P18505 2/20 0.33
GABRG2 P18507 2/20 0.33
GABRB3 P28472 2/20 0.33
GABRA5 P31644 2/20 0.33
GABRA3 P34903 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8669713 1.00 HCAR2 (0.59) HCAR2ALDH1A1KDM4EMAPTTDP1
SCHEMBL2219863 0.92 HCAR2 (0.45) HCAR2TSHRKEAP1NFE2L2ATM
SCHEMBL1404355 0.92 HCAR2 (0.45) HCAR2TSHRKEAP1NFE2L2ATM
SCHEMBL26393493 0.85 HCAR2 (0.39) HCAR2TSHRKEAP1NFE2L2ATM
SCHEMBL30100815 0.85 HCAR2 (0.59) HCAR2ALDH1A1GAATSHRTP53
SCHEMBL30268 0.85 HCAR2 (0.59) HCAR2ALDH1A1GAATSHRTP53
SCHEMBL246950 0.81 HCAR2 (0.55) HCAR2ALDH1A1KDM4EMAPTTDP1
SCHEMBL8418080 0.80 TSHR (0.39) HCAR2ALDH1A1MAPTTDP1TSHR
SCHEMBL8418077 0.80 TSHR (0.39) HCAR2ALDH1A1MAPTTDP1TSHR
Fumaric Acid SCHEMBL28457704 0.80 HCAR2 (0.53) HCAR2ALDH1A1GAATSHRATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3710544-B1 HYDROSILYLATION-CURABLE SILICONE COMPOSITION DOW SILICONES CORP (US) 2021-08-11 EP claimed
US-5836390-A Method for formation of subsurface barriers using viscous colloids THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-11-17 US claimed
CN-122011778-A Gel-type thermal interface material 霍尼韦尔国际公司 2026-05-12 CN disclosed
US-12497537-B2 Method of producing fluorosilicone rubber laminate, and fluorosilicone rubber laminate DOW TORAY CO., LTD. (JP) 2025-12-16 US disclosed
CN-120129721-A Curable organopolysiloxane composition and laminate 陶氏东丽株式会社 2025-06-10 CN disclosed
CN-119894982-A Thermally conductive silicone composition 美国陶氏有机硅公司 2025-04-25 CN disclosed
CN-113950513-B Heat conductive silicone composition 美国陶氏有机硅公司 2024-11-05 CN disclosed
CN-118895050-A Peelable thermogels 霍尼韦尔国际公司 2024-11-05 CN disclosed
US-12011904-B2 Production method for laminate of fluorosilicone rubber and silicone rubber DOW TORAY CO., LTD. (JP) 2024-06-18 US disclosed
US-20240174815-A1 ORGANOPOLYSILOXANE COMPOSITION DOW TORAY CO LTD (JP) 2024-05-30 US disclosed
WO-2024106246-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITION AND LAYERED PRODUCT ダウ・東レ株式会社 2024-05-23 WO disclosed
EP-3757186-A1 SILICONE PRESSURE-SENSITIVE ADHESIVE COMPOSITION AND LAYERED PRODUCT Dow Toray Co., Ltd. (JP) 2020-12-30 EP disclosed
CN-111868206-A Gel-type thermal interface material 霍尼韦尔国际公司 2020-10-30 CN disclosed
US-20200332122-A1 HYDROSILYLATION-CURABLE SILICONE COMPOSITION U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2020-10-22 US disclosed
CN-111670235-A Adhesive film 陶氏东丽株式会社 2020-09-15 CN disclosed
CN-111615544-A Silicone pressure sensitive adhesive composition and layered product 陶氏东丽株式会社 2020-09-01 CN disclosed
CN-111373013-A Peelable thermal gel 霍尼韦尔国际公司 2020-07-03 CN disclosed
CN-111344369-A Hydrosilylation-curable silicone composition 美国陶氏有机硅公司 2020-06-26 CN disclosed
WO-2020022407-A1 SILICONE RUBBER COMPOSITION AND PRODUCTION METHOD FOR LAMINATE OF FLUOROSILICONE RUBBER AND SILICONE RUBBER ダウ・東レ株式会社 2020-01-30 WO disclosed
WO-2020022406-A1 PRODUCTION METHOD FOR LAMINATE OF FLUOROSILICONE RUBBER AND SILICONE RUBBER ダウ・東レ株式会社 2020-01-30 WO disclosed