Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 8/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2219863 | 1.00 | HCAR2 (0.45) | HCAR2KEAP1NFE2L2ATMTSHR | |
| SCHEMBL8669713 | 0.92 | HCAR2 (0.59) | HCAR2KEAP1NFE2L2ATMTSHR | |
| SCHEMBL8669718 | 0.92 | HCAR2 (0.59) | HCAR2KEAP1NFE2L2ATMTSHR | |
| SCHEMBL26393493 | 0.92 | HCAR2 (0.39) | HCAR2KEAP1NFE2L2ATMTSHR | |
| SCHEMBL8418077 | 0.87 | TSHR (0.39) | HCAR2KEAP1NFE2L2ATMTSHR | |
| SCHEMBL8418080 | 0.87 | TSHR (0.39) | HCAR2KEAP1NFE2L2ATMTSHR | |
| SCHEMBL35727 | 0.85 | HCAR2 (0.33) | HCAR2MEN1KMT2A | |
| SCHEMBL57563 | 0.83 | TSHR (0.50) | TSHR | |
| SCHEMBL18418525 | 0.79 | HCAR2 (0.50) | HCAR2KEAP1NFE2L2ATMTSHR | |
| SCHEMBL25394391 | 0.78 | TSHR (0.33) | TSHRMEN1KMT2ACHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710544-B1 | HYDROSILYLATION-CURABLE SILICONE COMPOSITION | DOW SILICONES CORP (US) | 2021-08-11 | — | — | EP | claimed |
| US-6300426-B1 | IMPARTS TO THE SURFACES OF VARIOUS SUBSTRATES, SUCH AS PAPER, SYNTHETIC RESIN FILM, OR METAL FOIL, RELEASE PROPERTIES RELATIVE TO TACKY SUBSTANCES | DOW CORNING TORAY SILICONE COMPANY, LTD. (JP) | 2001-10-09 | — | — | US | claimed |
| US-6124419-A | A RELEASE MODIFIER COMPRISING AN ALKENYL FUNCTIONAL POLYORGANOSILOXANE AND A BRANCHED OLEFIN USEFUL IN RELEASE PRESSURE SENSITIVE ADHESIVES FROM A VARIETY OF SUBSTRATES | DOW CORNING, LIMITED (GB) | 2000-09-26 | — | — | US | claimed |
| EP-0980903-A2 | Release modifier compositions | DOW CORNING CORPORATION (US) | 2000-02-23 | — | — | EP | claimed |
| US-5836390-A | Method for formation of subsurface barriers using viscous colloids | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-11-17 | — | — | US | claimed |
| EP-0186439-B1 | HEAT-CURABLE SILICONE COMPOSITIONS, USE THEREOF AND STABILIZER THEREFOR | DOW CORNING CORPORATION (US) | 1992-07-29 | — | — | EP | claimed |
| US-5125998-A | Adding mixture of catalyst and inhibitor to organosilicon compound | DOW CORNING CORPORATION (US) | 1992-06-30 | — | — | US | claimed |
| EP-0288869-B1 | SILOXANE WATER BLOCK FOR ELECTRICAL CABLES | DOW CORNING CORPORATION (US) | 1992-06-03 | — | — | EP | claimed |
| US-4980440-A | Curable blend with metal-containing hydrosilation catalyst and catalyst inhibitor | DOW CORNING CORPORATION (US) | 1990-12-25 | — | — | US | claimed |
| US-4978694-A | STABILITY | DOW CORNING CORPORATION (US) | 1990-12-18 | — | — | US | claimed |
| US-4961961-A | CROSSLINKED POLYSILOXANE | DOW CORNING CORPORATION (US) | 1990-10-09 | — | — | US | claimed |
| US-4845309-A | CONTROLLING VISCOSITY USING A CROSSLINKED POLYSILOXANE | DOW CORNING CORPORATION (US) | 1989-07-04 | — | — | US | claimed |
| EP-0288869-A1 | Siloxane water block for electrical cables | DOW CORNING CORPORATION (US) | 1988-11-02 | — | — | EP | claimed |
| EP-0186439-A2 | Heat-curable silicone compositions, use thereof and stabilizer therefor | DOW CORNING CORPORATION (US) | 1986-07-02 | — | — | EP | claimed |
| US-4562096-A | Heat-curable silicone compositions, use thereof and stabilizer therefor | DOW CORNING CORPORATION (US) | 1985-12-31 | — | — | US | claimed |
| JP-1034948-A | — | — | None | — | — | JP | disclosed |
| US-20260132325-A1 | THERMALLY CONDUCTIVE SILICONE COMPOSITION | DOW SILICONES CORP (US) | 2026-05-14 | — | — | US | disclosed |
| US-4609574-A | METAL-CATALYZED HYDROSILATION | DOW CORNING CORPORATION (US) | 1986-09-02 | — | — | US | disclosed |
| EP-0186439-A2 | Heat-curable silicone compositions, use thereof and stabilizer therefor | DOW CORNING CORPORATION (US) | 1986-07-02 | — | — | EP | disclosed |
| US-4562096-A | Heat-curable silicone compositions, use thereof and stabilizer therefor | DOW CORNING CORPORATION (US) | 1985-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260132325-A1 | THERMALLY CONDUCTIVE SILICONE COMPOSITION | SMCHD1, SMC1A, SMC2 | HCAR2 3102/4885KEAP1 3989/4885NFE2L2 4498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.