SCHEMBL8669741

SCHEMBL8669741

NC(=O)NC(=O)Oc1ccc(O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.54
MAPT P10636 3/20 0.54
KDM4E B2RXH2 2/20 0.54
GLA P06280 2/20 0.54
BLM P54132 2/20 0.54
GFER P55789 2/20 0.54
THRB P10828 1/20 0.54
CASP6 P55212 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
PARP10 Q53GL7 1/20 0.46
PEPD P12955 1/20 0.45
ELANE P08246 2/20 0.41
XBP1 P17861 1/20 0.40
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39
PRSS1 P07477 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2186384 0.82 SLC1A3 (0.50) GAAMAPTKDM4EGFERTHRB
SCHEMBL5516916 0.79 GAA (0.58) GAAMAPTKDM4EGLABLM
SCHEMBL11416881 0.77 MGLL (0.55) GAAMAPTKMT2AMEN1ALDH1A1
SCHEMBL348122 0.76 MEN1 (0.54) GAAMAPTKDM4EGLABLM
SCHEMBL27513052 0.75 KDM4E (0.53) GAAMAPTKDM4EGLABLM
SCHEMBL28715947 0.75 GAA (0.53) GAAMAPTKDM4EGLABLM
SCHEMBL11058387 0.73 MAPT (0.51) GAAMAPTKDM4EGLABLM
SCHEMBL5783639 0.72 KMT2A (0.43) GAAMAPTKDM4EGLABLM
SCHEMBL5683906 0.71 MEN1 (0.52) GAAMAPTKDM4EGLABLM
SCHEMBL10356467 0.71 ESR2 (0.52) GAAMAPTKDM4EGLABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5747417-A CARBAMOYLOXYPHENYL CARBAMATE HERBICIDE, OIL-IN-WATER EMULSION HOECHST SCHERING AGREVO GMBH (DE) 1998-05-05 US claimed