Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MDM4 | O15151 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8671316 | 0.90 | MAPT (0.40) | MAPTTDP2PAX8HKDC1TLR9 | |
| SCHEMBL8667373 | 0.86 | HSP90AA1 (0.52) | MAPTTDP2PAX8HKDC1TLR9 | |
| SCHEMBL8666822 | 0.85 | MAPT (0.52) | MAPTTDP2PAX8HKDC1TLR9 | |
| SCHEMBL8108508 | 0.83 | MAPT (0.43) | MAPTTDP2PAX8HKDC1TLR9 | |
| SCHEMBL8102645 | 0.83 | TDP2 (0.60) | MAPTTDP2PAX8HKDC1TLR9 | |
| SCHEMBL8667530 | 0.81 | TDP2 (0.51) | MAPTTDP2PAX8HKDC1TLR9 | |
| SCHEMBL8100811 | 0.80 | HSP90AA1 (0.46) | MAPTTDP2PAX8HKDC1TLR9 | |
| SCHEMBL8668060 | 0.79 | TDP2 (0.42) | MAPTTDP2PAX8HKDC1TLR9 | |
| SCHEMBL8669717 | 0.79 | MAPT (0.40) | MAPTTDP2PAX8HKDC1TLR9 | |
| SCHEMBL8669425 | 0.77 | HSP90AA1 (0.51) | MAPTTDP2PAX8HKDC1TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882706-A1 | Cell adhesion inhibitors | ELI LILLY AND COMPANY (US) | 1998-12-09 | — | — | EP | disclosed |