Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 14/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.60 |
| ▸ | POLB | P06746 | 7/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | CCR6 | P51684 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | HTT | P42858 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14067864 | 0.88 | MEN1 (0.68) | MEN1KMT2APOLBNPSR1SMN1; SMN2 | |
| SCHEMBL8669762 | 0.87 | MEN1 (0.61) | MEN1KMT2APOLBNPSR1SMN1; SMN2 | |
| SCHEMBL8664264 | 0.82 | KDM4E (0.58) | MEN1KMT2APOLBLMNAALDH1A1 | |
| SCHEMBL8672555 | 0.82 | MEN1 (0.54) | MEN1KMT2APOLBNPSR1SMN1; SMN2 | |
| SCHEMBL29903439 | 0.80 | MEN1 (0.68) | MEN1KMT2APOLBNPSR1SMN1; SMN2 | |
| SCHEMBL10261656 | 0.80 | MEN1 (0.68) | MEN1KMT2APOLBNPSR1SMN1; SMN2 | |
| SCHEMBL8670977 | 0.79 | FTO (0.63) | MEN1KMT2APOLBPABPC1RAB9A | |
| SCHEMBL8031989 | 0.79 | HEXA (0.69) | MEN1KMT2APOLBNPSR1SMN1; SMN2 | |
| SCHEMBL14560563 | 0.78 | MEN1 (0.76) | MEN1KMT2APOLBNPSR1SMN1; SMN2 | |
| SCHEMBL10018568 | 0.77 | MEN1 (0.68) | MEN1KMT2APOLBNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789418-A | Bis-naphthalimides for the treatment of cancer | BASF AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |