Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | KHK | P50053 | 2/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8670989 | 0.99 | TP53 (0.38) | TP53IL4I1PARP1KHKSSTR1 | |
| SCHEMBL8666646 | 0.84 | PARP1 (0.33) | PARP1SSTR1SSTR4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8670945 | 0.83 | PARP1 (0.33) | PARP1SSTR1SSTR4MEN1KMT2A | |
| SCHEMBL8670586 | 0.83 | CHRM2 (0.32) | SSTR1SSTR4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8480750 | 0.78 | KMT2A (0.36) | KHKSSTR1SSTR4MEN1KMT2A | |
| SCHEMBL8668017 | 0.77 | SLC6A2 (0.33) | SSTR1SSTR4HRH1 | |
| Hydrochloric Acid SCHEMBL8670960 | 0.76 | SLC6A2 (0.33) | SSTR1SSTR4HRH1 | |
| SCHEMBL8672255 | 0.70 | TP53 (0.36) | TP53KHK | |
| Hydrochloric Acid SCHEMBL8672245 | 0.69 | TP53 (0.35) | TP53KHK | |
| SCHEMBL8669845 | 0.69 | TP53 (0.39) | TP53PARP1KHKSSTR1SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814636-A | TREATMENT AND PROPHYLAXIS OF THROMBOTIC DISEASES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1998-09-29 | — | — | US | disclosed |