Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.37 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | KHK | P50053 | 4/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8670984 | 0.99 | TP53 (0.39) | TP53SSTR4SSTR1PARP1KHK | |
| SCHEMBL8666641 | 0.83 | SSTR4 (0.37) | SSTR4SSTR1PARP1KHKHRH1 | |
| SCHEMBL8670582 | 0.82 | SSTR4 (0.36) | SSTR4SSTR1KHKHRH1 | |
| Hydrochloric Acid SCHEMBL8670941 | 0.82 | SSTR4 (0.36) | SSTR4SSTR1PARP1HRH1EPHX1 | |
| SCHEMBL8482988 | 0.78 | SSTR4 (0.39) | SSTR4SSTR1KHKHRH1 | |
| Hydrochloric Acid SCHEMBL8480749 | 0.77 | SSTR4 (0.39) | SSTR4SSTR1KHKHRH1 | |
| SCHEMBL8668015 | 0.76 | SSTR4 (0.38) | SSTR4SSTR1PARP1KHKHRH1 | |
| Hydrochloric Acid SCHEMBL8670955 | 0.75 | SSTR4 (0.38) | SSTR4SSTR1PARP1KHKHRH1 | |
| SCHEMBL8670654 | 0.70 | ITGB3 (0.35) | SSTR4SSTR1HTR2C | |
| SCHEMBL8669847 | 0.69 | TP53 (0.38) | TP53SSTR4SSTR1PARP1KHK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814636-A | TREATMENT AND PROPHYLAXIS OF THROMBOTIC DISEASES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1998-09-29 | — | — | US | disclosed |