Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 2/20 | 0.32 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665228 | 0.87 | BRAF (0.34) | BRAFKDRMAPK14TNNI3K | |
| SCHEMBL8666414 | 0.87 | BRAF (0.34) | BRAFKDRMAPK14TNNI3K | |
| SCHEMBL8665890 | 0.87 | KDR (0.34) | BRAFKDRMAPK14TNNI3K | |
| SCHEMBL8670005 | 0.87 | SCN9A (0.35) | BRAFKDRMAPK14TNNI3KSCN9A | |
| SCHEMBL8666832 | 0.86 | BRAF (0.33) | BRAFKDRMAPK14TNNI3KL3MBTL1 | |
| SCHEMBL8665290 | 0.85 | HPGD (0.38) | BRAFKDRMAPK14TNNI3KSCN9A | |
| SCHEMBL8668648 | 0.81 | KDR (0.34) | BRAFKDRMAPK14TNNI3K | |
| SCHEMBL8672951 | 0.79 | KMT2A (0.34) | BRAFKDRMAPK14TNNI3KKMT2A | |
| SCHEMBL8669834 | 0.78 | BRAF (0.39) | BRAFKDRMAPK14TNNI3KSCN9A | |
| SCHEMBL8667523 | 0.71 | EGFR (0.36) | BRAFKDRMAPK14TNNI3KKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723412-A | HERBICIDES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-03-03 | — | — | US | disclosed |