Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665228 | 0.84 | BRAF (0.34) | BRAFKDRMAPK14TNNI3KSLC22A12 | |
| SCHEMBL8666414 | 0.79 | BRAF (0.34) | BRAFKDRMAPK14TNNI3K | |
| SCHEMBL8665890 | 0.79 | KDR (0.34) | BRAFKDRMAPK14TNNI3KKDM4E | |
| SCHEMBL8670005 | 0.79 | SCN9A (0.35) | BRAFKDRMAPK14TNNI3KSCN9A | |
| SCHEMBL8669895 | 0.78 | BRAF (0.33) | BRAFKDRMAPK14TNNI3KSCN9A | |
| SCHEMBL8666832 | 0.78 | BRAF (0.33) | BRAFKDRMAPK14TNNI3K | |
| SCHEMBL8665290 | 0.77 | HPGD (0.38) | BRAFKDRMAPK14TNNI3KSCN9A | |
| SCHEMBL8668430 | 0.77 | BRAF (0.38) | BRAFKDRMAPK14TNNI3KHTR2C | |
| SCHEMBL8668648 | 0.74 | KDR (0.34) | BRAFKDRMAPK14TNNI3KHTR2C | |
| SCHEMBL8740250 | 0.73 | NFE2L2 (0.43) | NR1H3NR1H2SLC22A12NFE2L2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723412-A | HERBICIDES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-03-03 | — | — | US | disclosed |