Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 14/20 | 0.46 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8671124 | 0.89 | TACR1 (0.46) | TACR1SMN1; SMN2 | |
| SCHEMBL8673191 | 0.88 | TACR1 (0.48) | TACR1 | |
| SCHEMBL8671580 | 0.83 | TACR1 (0.49) | TACR1GAAUSP2TSHRSMN1; SMN2 | |
| SCHEMBL8673617 | 0.83 | TACR1 (0.49) | TACR1GAASMN1; SMN2 | |
| SCHEMBL8675298 | 0.82 | TACR1 (0.47) | TACR1USP2TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL8673600 | 0.82 | TACR1 (0.47) | TACR1USP2TSHRSMN1; SMN2 | |
| SCHEMBL8674849 | 0.82 | CCR2 (0.48) | TACR1 | |
| SCHEMBL8673212 | 0.81 | TACR1 (0.44) | TACR1TSHR | |
| SCHEMBL8672852 | 0.81 | TACR1 (0.49) | TACR1 | |
| SCHEMBL8671044 | 0.81 | TACR1 (0.46) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708006-A | ANTIINFLAMMATORY AGENTS | BOEHRINGER INGELHEIM KG (DE) | 1998-01-13 | — | — | US | disclosed |
| US-5696123-A | ALPHA-PIPERAZINYL BENZYL COMPOUND AS TACHYKININ ANTAGONIST TREATING ASTHMA, BRONCHITIS, SKIN DISORDER, EYE DISEASE, HEADACHE, GASTROINTESTINAL DISORDER | BOEHRINGER INGELHEIM KG (DE) | 1997-12-09 | — | — | US | disclosed |