⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15865362 | 0.81 | CYP2D6 (0.39) | — | |
| SCHEMBL11852461 | 0.79 | — | — | |
| SCHEMBL8995332 | 0.78 | TSHR (0.52) | — | |
| SCHEMBL10401351 | 0.77 | — | — | |
| SCHEMBL11443506 | 0.77 | — | — | |
| SCHEMBL10364270 | 0.74 | — | — | |
| SCHEMBL11444933 | 0.74 | — | — | |
| SCHEMBL27096231 | 0.74 | CYP2D6 (0.38) | — | |
| SCHEMBL8725908 | 0.71 | CYP2D6 (0.45) | — | |
| SCHEMBL2223767 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190100534-A1 | Cephem Compounds with Latent Reactive Groups | GLADIUS PHARMACEUTICALS INC (CA) | 2019-04-04 | — | — | US | disclosed |
| US-9642869-B2 | Boronic acid derivatives and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2017-05-09 | — | — | US | disclosed |
| US-9642869-B2 | Boronic acid derivatives and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2017-05-09 | — | — | US | disclosed |
| US-9428528-B2 | Phenicol antibacterials | ZOETIS SERVICES LLC (US) | 2016-08-30 | — | — | US | disclosed |
| US-20160194342-A1 | PHENICOL ANTIBACTERIALS | ZOETIS SERVICES LLC (US) | 2016-07-07 | — | — | US | disclosed |
| CN-103517907-B | Volution isoxazolines derivative as antiparasitic | 硕腾服务有限责任公司 | 2016-07-06 | — | — | CN | disclosed |
| EP-2683723-B1 | SPIROCYCLIC ISOXAZOLINE DERIVATIVES AS ANTIPARASITIC AGENTS | ZOETIS SERVICES LLC (US) | 2016-05-25 | — | — | EP | disclosed |
| US-9340564-B2 | Phenicol antibacterials | ZOETIS SERVICES LLC (US) | 2016-05-17 | — | — | US | disclosed |
| US-20150266910-A1 | PHENICOL ANTIBACTERIALS | ZOETIS SERVICES LLC (US) | 2015-09-24 | — | — | US | disclosed |
| US-9101638-B2 | Boronic acid derivatives and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2015-08-11 | — | — | US | disclosed |
| US-4158733-A | 7β-Acyloxy-3-acetoxymethyl cephalosporins | SMITHKLINE CORPORATION (US) | 1979-06-19 | — | — | US | disclosed |
| US-4131734-A | 7β-Acyloxy-3-heterocyclicthiomethyl cephalosporins | SMITHKLINE CORPORATION (US) | 1978-12-26 | — | — | US | disclosed |
| US-4103086-A | 8-Oxo-4-thia-1-azabicyclo (4.2.0)-oct-2-ene derivatives | SMITHKLINE CORPORATION (US) | 1978-07-25 | — | — | US | disclosed |
| US-4101657-A | Cephamycins as antibacterial agents | SMITHKLINE CORPORATION (US) | 1978-07-18 | — | — | US | disclosed |
| US-4072674-A | FOR CEPHALOSPORIN CONGENERS | SMITHKLINE CORPORATION (US) | 1978-02-07 | — | — | US | disclosed |
| US-4059578-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1977-11-22 | — | — | US | disclosed |
| US-4020057-A | 7β-Acyloxy cephalosporins | SMITHKLINE CORPORATION (US) | 1977-04-26 | — | — | US | disclosed |
| US-3943131-A | BACTERICIDE | SMITHKLINE CORPORATION (US) | 1976-03-09 | — | — | US | disclosed |
| US-3943127-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1976-03-09 | — | — | US | disclosed |
| US-3943128-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1976-03-09 | — | — | US | disclosed |