Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.34 |
| ▸ | PTGFR | P43088 | 4/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7517233 | 1.00 | SOAT1 (0.37) | SOAT1MEN1FAAHTP53CYP1A2 | |
| SCHEMBL7517738 | 0.90 | TBXA2R (0.42) | MEN1KMT2ALMNAABCC4HPGD | |
| SCHEMBL8938445 | 0.89 | — | — | |
| SCHEMBL8671901 | 0.89 | — | — | |
| SCHEMBL7511928 | 0.89 | — | — | |
| SCHEMBL11787749 | 0.86 | ALDH1A1 (0.45) | KDM4ELMNATBXA2RPTGER3ALDH1A1 | |
| SCHEMBL11792606 | 0.86 | ALDH1A1 (0.45) | KDM4ELMNATBXA2RPTGER3ALDH1A1 | |
| SCHEMBL8668224 | 0.86 | CNR1 (0.35) | CNR1LMNAABCC4HPGDTBXA2R | |
| SCHEMBL9179064 | 0.86 | CNR1 (0.35) | CNR1LMNAABCC4HPGDTBXA2R | |
| SCHEMBL7515545 | 0.86 | CNR1 (0.35) | CNR1LMNAABCC4HPGDTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773654-A | 7-(5-substituted cyclopentyl) and (5-substituted cyclopentenyl) heptyl alcohols, heptylamines and heptanoic acid amides, and method of lowering intraocular pressure in the eye of a mammal by administration of these compounds | ALLERGAN (US) | 1998-06-30 | — | — | US | disclosed |
| US-5674910-A | 7-(5-substituted cyclopentyl) and (5-substituted cyclopentenyl) heptyl alcohols, heptylamines and heptanoic acid amides, and method of lowering intraocular pressure in the eye of a mammal by administration of these novel compounds | ALLERGAN (US) | 1997-10-07 | — | — | US | disclosed |