Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.50 |
| ▸ | CCR3 | P51677 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL949225 | 0.79 | CYP1A2 (0.63) | L3MBTL3L3MBTL1ALDH1A1KDM4ELMNA | |
| SCHEMBL16226347 | 0.77 | CHRM2 (0.54) | L3MBTL3L3MBTL1CHRM2CHRM1SLC18A3 | |
| SCHEMBL16226856 | 0.77 | CHRM2 (0.54) | L3MBTL3L3MBTL1CHRM2CHRM1SLC18A3 | |
| SCHEMBL7616842 | 0.77 | GAA (0.65) | CHRM2CHRM1CCR3ALDH1A1OPRD1 | |
| SCHEMBL16226855 | 0.77 | CHRM2 (0.54) | L3MBTL3L3MBTL1CHRM2CHRM1SLC18A3 | |
| SCHEMBL11811001 | 0.77 | CHRM2 (0.61) | L3MBTL3L3MBTL1CHRM2CHRM1SLC18A3 | |
| SCHEMBL16226532 | 0.77 | CHRM2 (0.54) | L3MBTL3L3MBTL1CHRM2CHRM1SLC18A3 | |
| SCHEMBL16226533 | 0.77 | CHRM2 (0.54) | L3MBTL3L3MBTL1CHRM2CHRM1SLC18A3 | |
| SCHEMBL945419 | 0.77 | CYP2D6 (0.61) | L3MBTL3L3MBTL1CHRM2CHRM1ALDH1A1 | |
| SCHEMBL16226689 | 0.76 | TSHR (0.68) | CHRM1CCR3OPRD1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708006-A | ANTIINFLAMMATORY AGENTS | BOEHRINGER INGELHEIM KG (DE) | 1998-01-13 | — | — | US | disclosed |
| US-5696123-A | ALPHA-PIPERAZINYL BENZYL COMPOUND AS TACHYKININ ANTAGONIST TREATING ASTHMA, BRONCHITIS, SKIN DISORDER, EYE DISEASE, HEADACHE, GASTROINTESTINAL DISORDER | BOEHRINGER INGELHEIM KG (DE) | 1997-12-09 | — | — | US | disclosed |