Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | GABRP | O00591 | 2/20 | 0.46 |
| ▸ | GABRD | O14764 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.46 |
| ▸ | GABRE | P78334 | 2/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583489 | 0.82 | CYP1A2 (0.50) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL198528 | 0.82 | CYP1A2 (0.50) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8583491 | 0.82 | CYP1A2 (0.50) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL198527 | 0.82 | CYP1A2 (0.50) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| Hydrochloric Acid SCHEMBL2257624 | 0.80 | CYP1A2 (0.48) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| Hydrochloric Acid SCHEMBL1934550 | 0.80 | CYP1A2 (0.48) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2984816 | 0.80 | CYP1A2 (0.48) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2984814 | 0.80 | CYP1A2 (0.48) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL4779396 | 0.79 | CYP1A2 (0.43) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL16666108 | 0.79 | CYP1A2 (0.43) | CYP1A2GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024198046-A1 | BIOMARKER AND SYSTEM FOR PREDICTING EVOLUTION INTO ACLF OR DEATH OF ACLF PATIENT, AND USES THEREOF | 上海甘宁医疗科技有限公司 | 2024-10-03 | — | — | WO | claimed |
| EP-0525836-B1 | Assay method using novel NAD synthetase | ASAHI CHEMICAL IND (JP) | 1998-12-09 | — | — | EP | claimed |
| US-5206146-A | Incubating specimen with NAD synthetase to generate NAD, performing coenzyme cycling reaction, measuring consumed or generated component | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1993-04-27 | — | — | US | claimed |
| EP-0525836-A2 | Assay method using novel NAD synthetase | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1993-02-03 | — | — | EP | claimed |
| EP-0260137-A2 | Assay method using novel NAD synthetase and a process for production of the enzyme | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1988-03-16 | — | — | EP | claimed |
| CN-119510604-A | Biomarker for predicting whether ACLF patient will die, system and application thereof | 上海甘宁医疗科技有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-119470683-A | Biomarker for predicting whether ACLF will be formed, system and application thereof | 上海甘宁医疗科技有限公司 | 2025-02-18 | — | — | CN | disclosed |
| WO-2024198046-A1 | BIOMARKER AND SYSTEM FOR PREDICTING EVOLUTION INTO ACLF OR DEATH OF ACLF PATIENT, AND USES THEREOF | 上海甘宁医疗科技有限公司 | 2024-10-03 | — | — | WO | disclosed |
| CN-117191963-B | Biomarkers, systems, and uses thereof for predicting whether progression to ACLF or mortality in ACLF patients will occur | 上海甘宁医疗科技有限公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-117191963-A | Biomarkers, systems, and uses thereof for predicting whether progression to ACLF or mortality in ACLF patients will occur | 上海甘宁医疗科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-116507349-A | Probiotic bacillus compositions and methods of use | 生物编辑有限责任公司 | 2023-07-28 | — | — | CN | disclosed |
| US-5206146-A | Incubating specimen with NAD synthetase to generate NAD, performing coenzyme cycling reaction, measuring consumed or generated component | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1993-04-27 | — | — | US | disclosed |
| US-4767712-A | CULTURE PRODUCT OF BACILLUS | TOYO JOZO KABUSHIKI KAISHA (JP) | 1988-08-30 | — | — | US | disclosed |