SCHEMBL198528

SCHEMBL198528

CN(C)[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.50
TET2 Q6N021 3/20 0.46
KDM4A O75164 2/20 0.46
KDM4C Q9H3R0 2/20 0.46
KDM2A Q9Y2K7 2/20 0.46
TET3 O43151 1/20 0.46
FOLH1 Q04609 9/20 0.44
GABRP O00591 2/20 0.44
GABRD O14764 2/20 0.44
GABRA1 P14867 2/20 0.44
GABRB1 P18505 2/20 0.44
GABRG2 P18507 2/20 0.44
GABRB3 P28472 2/20 0.44
GABRA5 P31644 2/20 0.44
GABRA3 P34903 2/20 0.44
GABRA2 P47869 2/20 0.44
GABRB2 P47870 2/20 0.44
GABRA4 P48169 2/20 0.44
GABRE P78334 2/20 0.44
GABRA6 Q16445 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL198527 1.00 CYP1A2 (0.50) CYP1A2TET2KDM4AKDM4CKDM2A
Hydrochloric Acid SCHEMBL1934550 0.98 CYP1A2 (0.48) CYP1A2TET2KDM4AKDM4CKDM2A
Hydrochloric Acid SCHEMBL2257624 0.98 CYP1A2 (0.48) CYP1A2TET2KDM4AKDM4CKDM2A
Sulfuric Acid SCHEMBL1521031 0.92 CYP1A2 (0.43) CYP1A2TET2KDM4AKDM4CKDM2A
Sulfuric Acid SCHEMBL1521033 0.92 CYP1A2 (0.43) CYP1A2TET2KDM4AKDM4CKDM2A
SCHEMBL15405381 0.86 LMNA (0.42) CYP1A2FOLH1
SCHEMBL2984814 0.84 CYP1A2 (0.48) CYP1A2TET2KDM4AKDM4CKDM2A
SCHEMBL2984816 0.84 CYP1A2 (0.48) CYP1A2TET2KDM4AKDM4CKDM2A
SCHEMBL14319857 0.84 GABRP (0.43) CYP1A2TET2KDM4AKDM4CKDM2A
SCHEMBL1082587 0.83 FFAR4 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117778530-A Method for adding preset joint to 5' end of single-stranded DNA 清华大学 2024-03-29 CN claimed
US-9657079-B2 Truncated GLP-1 derivatives and their therapeutical use NOVO NORDISK A/S (DK) 2017-05-23 US claimed
CN-105001108-A Optical pure 3,4-dimethyl glutamic acid derivative preparation method UNIV HEBEI SCIENCE & TECH 2015-10-28 CN claimed
EP-2190873-B1 TRUNCATED GLP-1 DERIVATIVES AND THEIR THERAPEUTICAL USE NOVO NORDISK AS (DK) 2015-07-22 EP claimed
US-9067977-B2 Peptides derivatized with A-B-C-D- and their therapeutical use NOVO NORDISK A/S (DK) 2015-06-30 US claimed
US-20140296131-A1 Truncated GLP-1 Derivatives and Their Therapeutical Use NOVO NORDISK A/S (DK) 2014-10-02 US claimed
US-20140011732-A1 Peptides Derivatized with A-B-C-D- and their Therapeutical Use NOVO NORDISK A/S (DK) 2014-01-09 US claimed
JP-2010538048-A 2010-12-09 JP claimed
EP-2258702-A2 Purified compositions of 10-Propargyl-10-Deazaaminopterin and method of using same in the treatment of tumors Sloan-Kettering Institute For Cancer Research (US) 2010-12-08 EP claimed
US-20100292133-A1 TRUNCATED GLP-1 DERIVATIES AND THEIR THERAPEUTICAL USE NOVO NORDISK A/S (DK) 2010-11-18 US claimed
EP-2190873-A1 TRUNCATED GLP-1 DERIVATIVES AND THEIR THERAPEUTICAL USE Novo Nordisk A/S (DK) 2010-06-02 EP claimed
EP-2190460-A1 PEPTIDES DERIVATIZED WITH A-B-C-D- AND THEIR THERAPEUTICAL USE Novo Nordisk A/S (DK) 2010-06-02 EP claimed
WO-2009030771-A1 PEPTIDES DERIVATIZED WITH A-B-C-D- AND THEIR THERAPEUTICAL USE NOVO NORDISK A/S (DK) 2009-03-12 WO claimed
WO-2009030774-A1 TRUNCATED GLP-1 DERIVATIVES AND THEIR THERAPEUTICAL USE NOVO NORDISK A/S (DK) 2009-03-12 WO claimed
EP-1891957-A1 Purified Compositions of 10-Propargyl-10-Deazaaminopterin and Methods of Using Same in the Treament of Tumors Sloan-Kettering Institute for Cancer Research (US) 2008-02-27 EP claimed
EP-0506207-B1 Pharmaceutical vehicles for reducing transdermal flux ACCESS PHARMA INC (US) 1999-11-17 EP claimed
EP-0872248-A2 Pharmaceutical vehicles for reducing transdermal flux Access Pharmaceuticals, Inc. (US) 1998-10-21 EP claimed
EP-0506207-A2 Pharmaceutical vehicles for reducing transdermal flux CHEMEX PHARMACEUTICALS, Inc. (US) 1992-09-30 EP claimed
US-4895727-A Using water soluble zinc compound CHEMEX PHARMACEUTICALS, INC. (US) 1990-01-23 US claimed
EP-0259133-A2 Use of organic buffers to reduce dehydroascorbic acid interference in analytical methods EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-03-09 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140011732-A1 Peptides Derivatized with A-B-C-D- and their Therapeutical Use GLP1R, IAPP, GIPR CYP1A2 3450/4885TET2 4544/4885KDM4A 3170/4885
US-20100292133-A1 TRUNCATED GLP-1 DERIVATIES AND THEIR THERAPEUTICAL USE GLP1R, GIPR, IAPP CYP1A2 3675/4885TET2 1250/4885KDM4A 331/4885
US-20140296131-A1 Truncated GLP-1 Derivatives and Their Therapeutical Use GLP1R, GIPR, IAPP CYP1A2 3577/4885TET2 1488/4885KDM4A 483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.